Three-dimensional reconstruction of human Neiguan point structure based on digitized virtual reality technology

doi:10.3969/j.issn.2095-4344.2013.48.001

Abstract

Abstract:

BACKGROUND: Based on the integration of virtual reality technology with acupoints, acupuncture can be expressed three-dimensionally.
OBJECTIVE: To explore the structure of points through reconstructing digitalized three-dimensional visualization of Neiguan (PC6) structure based on VOXEL-MAN and Micro-XCT.
METHODS: Muscles and other tissues adjacent with Neiguan (PC6) were segmented and merged based on the VOXEL-MAN system combined with the anatomical knowledge of acupoints; nerves and blood vessels were performed with three-dimensional reconstruction; the needle-inserting animation of Neiguan (PC6) was obtained by running script file. Three-dimensional visualization and virtual needle-inserting researches of Neiguan (PC6) were performed. Nature of the acupoints was detected by the Micro-XCT-200 machine additionally.
RESULTS AND CONCLUSION: The visualization of the anatomical structure of local Neiguan (PC6) was completed, and the localization and expression of Neiguan (PC6) in the digitized virtual human were realized. The Neiguan (PC6) structure was researched with Micro-XCT-200, and showed there was no new tissue. Local three-dimensional reconstruction of the acupoint structure could help to display the anatomical structure of acupoints and simulate the acupuncture process. It could also help to observe the relationship between the needle body and the surrounding tissues during needle-inserting, which supplying a good basis not only for exploring the security of needle-inserting, but also for improving the clinical effect of acupuncture. The research on the structure of acupoint Neiguan (PC6) by Micro-XCT-200 provides further experimental evidence for the hypothesis of three-dimensional acupoint.

Key words: anatomy, imaging, three-dimensional, acupuncture points, visible human projects

CLC Number:

R318

Liu Yan-xiang, Jiang Jun, Yan Zhen-guo, Guo Yi, Zhuang Tian-ge, Shao Shui-jin, Zhang Li-sheng, Liu Jia-lin. Three-dimensional reconstruction of human Neiguan point structure based on digitized virtual reality technology[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(48): 8301-8306.

Figures/Tables 3

References

[1] 王书诚.低频电脉冲治疗原发性高血压的效果研究[J].临床和实验医学杂志,2010,9(9):657-658.

[2] 王向英,张莉,王建成,等.针刺治疗假性球麻痹32例[J].江苏中医药,2006,27(9):61.

[3] 叶德宝,方剑乔,宋莹慧,等.内关穴经皮电刺激对偏头痛急性发作患者TCD的影响[J].浙江中医学院学报,2003,27(4):68-70.

[4] 温塘芳,陈云飞,刘凤梅,等.小剂量氟哌利多内关穴注射治疗术后顽固性呃逆临床观察[J].临床合理用药杂志,2009,2(5): 16-17.

[5] You Q, Yu H, Wu D,et al.Vitamin B6 points PC6 injection during acupuncture can relieve nausea and vomiting in patients with ovarian cancer.Int J Gynecol Cancer. 2009; 19(4):567-571.

[6] Wollaston DE, Xu X, Tokumaru O,et al.Patients with systemic sclerosis have unique and persistent alterations in gastric myoelectrical activity with acupressure to Neiguan point PC6.J Rheumatol.2005;32(3):494-501.

[7] Kim H, Park HJ, Han SM,et al.The effects of acupuncture stimulation at PC6 (Neiguan) on chronic mild stress-induced biochemical and behavioral responses.Neurosci Lett. 2009; 460(1):56-60.

[8] 易婧,杨莉,张彦妮.按压内关穴对皮试疼痛的影响[J].临床军医杂志,2007,35(5):777.

[9] 潘莉,潘贵书.电针内关穴对海洛因依赖大鼠心率变异性的影响[J].包头医学院学报,2008, 24(5):448-451.

[10] 蔡琛,吴俊梅,薛红,等.针灸治疗海洛因依赖选穴规律探究[J].成都医学院学报,2008,3(3):170-172.

[11] 徐德国,戴启刚,常加松.侧脑室注射P物质对心肌缺血调整作用的机理研究[J].辽宁中医药大学学报,2008,10(6):201-202.

[12] 王智君,李为民,Thomas Friedemann.针刺内关穴对正常麻醉大鼠血压的调节作用[J].上海针灸杂志,2009,28(3):175-178.

[13] 付平,贾建平,闵宝权.针刺内关穴对阿尔茨海默病脑功能磁共振成像的影响[J].中华神经科杂志,2005,38(2):118-119.

[14] Hübscher M, Vogt L, Banzer W.Laser needle acupuncture at Neiguan (PC6) does not mediate heart rate variability in young, healthy men.Photomed Laser Surg. 2007;25(1):21-25.

[15] GB/T 12346-2006,腧穴名称与定位[S].2006.

[16] 沈雪勇.经络腧穴学[M].北京:中国中医药出版社,2007:162-163

[17] 石学敏.针灸学[M].北京:中国中医药出版社,2007:82.

[18] 张吉.针灸学[M].北京:人民卫生出版社,2006:190-191.

[19] 严振国.经穴断面解剖图解(上肢部分)[M].上海:上海科学技术出版社,1983:84-85.

[20] Viceconti M, Clapworthy G, Van Sint Jan S.The Virtual Physiological Human - a European initiative for in silico human modelling.J Physiol Sci. 2008;58(7):441-446.

[21] Spitzer VM,Whitlock DG.人体断层解剖学彩色图谱[M].天津:天津科学技术出版社,2002: 122-190.

[22] 大卫•迪安,托马斯•赫伯纳. 人体断面解剖学与医学影像学图谱[M].郑州:河南科学技术出版社,2002:132-144.

[23] (英)韦尔(Jamie Weir),亚伯拉罕斯(Peter H. Abrahams)著.陈宏颉,高进喜,李敬成,等译.影像解剖图谱[M].3版.福州:福建科学技术出版社,2006:160-204.

[24] 主海文,刘有军,曾衍钧.血管图像分割技术的研究进展[J].北京生物医学工程,2005,24(2):155-159.

[25] 庄天戈,严振国.基于中医理念的穴位融合的三维可视人[J].中国基础科学,2004,6(1):26-29.

[26] Höhne KH, Pflesser B, Pommert A,et al.A realistic model of human structure from the visible human data.Methods Inf Med. 2001;40(2):83-89.

[27] Pommert A, Höhne KH, Pflesser B,et al.Creating a high-resolution spatial/symbolic model of the inner organs based on the Visible Human.Med Image Anal. 2001;5(3): 221-228.

[28] 沈雪勇.经络腧穴学[M].北京:中国中医药出版社,2007:289-296.

[29] Goldman N, Chen M, Fujita T,et al.Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture.Nat Neurosci. 2010;13(7):883-888.

[30] 丁光宏,魏瑚.经络实质的揭示是中医现代化的关键[J].世界科学技术-中医药现代化,2005, 7(5):107-112.

[31] 张迪,丁光宏,沈雪勇,等.针刺引起结缔组织效应的研究进展[J].针刺研究,2004,29(1):77- 80.

[32] 张维波,郭义,林玉英,等. 经络研究近50年回顾与今后研究方向[J].世界科学技术-中医药现代化,2005,7(5):99-104.

[33] 秦翊麟.图像分割及其在虚拟人肌肉识别与胸片特征辨识中的应用研究[D].上海:上海交通大学,2006:13-22.

[34] 单锦露,张绍祥,刘正津,等.中国数字化可视人女性盆腔的计算机三维重建[J].解剖学杂志,2005,28(3):337-339.

[35] Schiemann T, Tiede U, Höhne KH.Segmentation of the visible human for high-quality volume-based visualization.Med Image Anal. 1997;1(4):263-270.

[36] Spitzer VM, Whitlock DG.The Visible Human Dataset: the anatomical platform for human simulation.Anat Rec. 1998; 253(2):49-57.

[37] 宋岳涛,尹岭.中国数字人数据库的构建与数据资源共享[J].中国医学影像技术,2006,22(9): 1306-1309.

[38] GB12346-90.中华人民共和国国家标准•经穴部位[S].1990.

[39] 钟世镇.数字人和数字解剖学[M].济南:山东科学技术出版社, 2004: 561-591．

[40] 赵静,刘红菊,庄天戈,等.融合中医知识库的虚拟针灸三维浏览器[J].上海针灸杂志,2005, 24(2):29-32.

[41] 耿宁,李晓箐,易新竹,等.显微CT在牙体解剖数字化教学中的应用[J].国际口腔医学杂志, 2010,37(1):10-13.

[42] 陈方府,漆玉金,张雪竹.X射线显微CT成像的图像实时校正研究[J].核电子学与探测技术, 2009,29(4):910-913.

[43] 郭义.实验针灸学[M].北京:中国中医药出版社,2008:362-417.

[44] 王春田.基础医学实验动物操作基本技能[M].北京:中国医药科学技术出版社,2009:132-177.

[45] 邓月良.经络的研究[J].医学研究通讯,2003,32(2):26-27

[46] 原林,焦培峰,唐雷,等.中医经络理论的物质基础-结缔组织、筋膜和自体监控系统[J].中国基础科学,2005,7(3):44-47.

[47] 田宝俊,朱训生,章浩伟,等.基于运动控制针刺手法仪的工程研究[J].计算机工程与应用,2008, 44(20):206-207.

[48] Heng PA, Wong TT, Yang R,et al.Intelligent inferencing and haptic simulation for Chinese acupuncture learning and training.IEEE Trans Inf Technol Biomed. 2006;10(1):28-41.

[49] 刘文霞,王树杰,张继伟,等.虚拟现实技术在医学上的应用[J].生物医学工程学杂志, 2007,24(4):946-949.